Study of genetic variability in pigs after the traditional breeding program.
Identification of differentially expressed genes in pathways of cerebral neurotransmission of anovulatory mice.
Genotyping of SNPs associated with meat tenderness: comparison of two PCR-based methods.
Leptin (rs7799039) and solute carrier family 30 zinc transporter (rs13266634) polymorphisms in Euro-Brazilian pregnant women with gestational diabetes.
Polymorphisms in the leptin gene promoter in Brazilian beef herds.
Association study between single nucleotide polymorphisms in leptin and growth traits in Cyprinus carpio var. Jian
Leptin is a hormone that affects the regulation of body weight, energy expenditure, fat metabolism, food intake, and appetite. In this study, we cloned the jlLEP-A1 and jlLEP-A2 genes in Jian carp (Cyprinus carpio var. Jian) and performed an association analysis between identified polymorphisms and growth traits.
Prevalence of mutations in LEP, LEPR, and MC4R genes in individuals with severe obesity
Obesity is a major public health concern; despite evidence of high heritability, the genetic causes of obesity remain unclear. In this study, we assessed the presence of mutations in three genes involved in the hypothalamic leptin-melanocortin regulation pathway (leptin, LEP; leptin receptor, LEPR; and melanocortin-4 receptor, MC4R), which is important for energy homeostasis in the body, in a group of patients with severe obesity.
Relationship between serum leptin levels and non-small cell lung carcinoma: a meta-analysis
In this study, we analyzed the association between serum leptin levels and non-small cell lung carcinoma (NSCLC). By examining English and Chinese databases, we identified potential relevant studies for statistical analysis. Human-associated case-control studies evaluating the association between serum leptin levels and NSCLC according to the random-effect model were retrieved and extracted data were statistically analyzed.