Y. Zhao, Zhang, Y., Song, H. B., Wu, F., Wang, X. L., Sun, S. - C., Cui, T. X., and Tang, D. Q.
, “Proteomic analysis revealed the altered kidney protein profile of a Cyld knockout mouse model”
, vol. 14, pp. 5970-5978, 2015.
The aim of this study was to compare the proteomics pattern of the kidneys from Cyld knockout mice with that from normal mouse kidneys and establish a preliminary understanding of the role of Cyld in the kidney. Proteins from the kidneys of knockout Cyld mice and wild-type mice were extracted, isobaric tags for relative and absolute quantitation (iTRAQ) was performed, and the proteomics patterns of the two groups were compared. The genotypes of the mice were verified by polymerase chain reaction.