KCNE1

KCNE1 112G>A polymorphism and atrial fibrillation risk: a meta-analysis

H. G. Han, Wang, H. S., Yin, Z., Jiang, H., Fang, M., and Han, J., KCNE1 112G>A polymorphism and atrial fibrillation risk: a meta-analysis, vol. 13, pp. 8367-8377, 2014.

KCNE1, a membrane protein that spans the membrane once is responsible for modulating potassium channel functions and plays an important role in the etiology of arrhythmia. Emerging evidence indicates that a common polymorphism (112G>A; rs1805127 G>A) in the KCNE1 gene contributes to atrial fibrillation (AF) risk; however, these studies showed inconclusive results. In this meta-analysis, we derived a more precise estimation of the association between the KCNE1 112G>A polymorphism and AF risk.

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