KCNE1 112G>A polymorphism and atrial fibrillation risk: a meta-analysis
“KCNE1 112G>A polymorphism and atrial fibrillation risk: a meta-analysis”, vol. 13, pp. 8367-8377, 2014.,
KCNE1, a membrane protein that spans the membrane once is responsible for modulating potassium channel functions and plays an important role in the etiology of arrhythmia. Emerging evidence indicates that a common polymorphism (112G>A; rs1805127 G>A) in the KCNE1 gene contributes to atrial fibrillation (AF) risk; however, these studies showed inconclusive results. In this meta-analysis, we derived a more precise estimation of the association between the KCNE1 112G>A polymorphism and AF risk.