Correlative study between the JAK2V617F mutation and thrombosis in patients with myeloproliferative neoplasm
“Correlative study between the JAK2V617F mutation and thrombosis in patients with myeloproliferative neoplasm”, vol. 15, p. -, 2016.
, In this study, we investigated the correlation between the JAK2V617F mutation and thrombosis in patients with myeloproliferative neoplasm (MPN) using real-time fluorescence quantitative PCR. The incidence of thrombus was monitored and blood and coagulation were routinely assayed in patients with MPN. The JAK2V617F mutation was found in 8/68 individuals in the control group (11.8%); it was expressed in 44/68 patients with MPN (64.7%), suggesting that the rate of this mutation was significantly higher in patients with MPN than that in the control group.