Invasion

Influence of suppression of CapG gene expression by siRNA on the growth and metastasis of human prostate cancer cells

B. K. Li, Guo, K., Li, C. Y., Li, H. L., Zhao, P. P., Chen, K., and Liu, C. X., Influence of suppression of CapG gene expression by siRNA on the growth and metastasis of human prostate cancer cells, vol. 14, pp. 15769-15778, 2015.

This study investigated CapG gene expression in prostate cancer cell lines; in addition, we explored the effects of CapG suppression on DU145 cell growth, and the underlying mechanism with which CapG affects DU145 cell growth and invasiveness. The expression of CapG and 18 related genes in DU145 cells was analyzed by flow cytometry, quantitative polymerase chain reaction (qPCR), CCK8 assay, western blot, and the trans-well assay. DU145 cells were transfected with designed small interfering RNA (siRNA). CapG expression was quantified by qPCR and western blot.

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