Interleukin 6

Interleukin-6 (IL-6) -174G/C genomic polymorphism contribution to the risk of coronary artery disease in a Chinese population

L. Mao, Geng, G. Y., Han, W. J., Zhao, M. H., Wu, L., Liu, H. L., Mao, L., Geng, G. Y., Han, W. J., Zhao, M. H., Wu, L., and Liu, H. L., Interleukin-6 (IL-6) -174G/C genomic polymorphism contribution to the risk of coronary artery disease in a Chinese population, vol. 15, p. -, 2016.

To investigate the role of IL-6 polymorphism (-174G/C and -572C/G) in the development of coronary artery disease (CAD), CAD patients (224) and control subjects (260) were recruited between January 2012 and December 2014. Genotyping at IL-6 -174G/C and -572C/G was conducted via polymerase chain reaction coupled to restriction fragment length polymorphism. Results indicated that several disease risk factors were significantly higher in CAD patients as compared to the control subjects.

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