Interleukin 4

Association between the interleukin 4 gene -590C>T promoter polymorphism and asthma in Xinjiang Uighur children

J. H. Zhang, Zhou, G. H., Wei, T. T., Chang, Z. S., Zhang, J. H., Zhou, G. H., Wei, T. T., and Chang, Z. S., Association between the interleukin 4 gene -590C>T promoter polymorphism and asthma in Xinjiang Uighur children, vol. 15, p. -, 2016.

We investigated the association between the interleukin 4 gene (IL-4) -590C>T polymorphism and forced expiratory volume in one second (FEV1) values, immunoglobulin E (IgE) levels, and susceptibility to asthma in Uighur children. IL-4 -590C>T frequencies were analyzed in 38 bronchial asthmatic patients and 35 non-asthmatic controls. Polymerase chain reaction and direct sequencing were applied to determine the residue at position -590 of IL-4.

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