Interleukin-10 gene

Interleukin-10 gene promoter polymorphism and risk of liver cirrhosis

Y. Liu, Yu, M. C., Zhang, A. Q., Wang, Y. B., Jiang, K., and Dong, J. H., Interleukin-10 gene promoter polymorphism and risk of liver cirrhosis, vol. 14, pp. 1229-1234, 2015.

We conducted a hospital-based case-control study to assess the association between IL-10-592 A/C, IL-10-819 C/T, and IL-10-1082 A/G polymorphisms and the risk of liver cirrhosis in a Chinese population. This 1:1-matched case-control study included 192 patients from the Chinese PLA General Hospital. Genotypes of IL-10-592 A/C, IL-10-819 C/T, and IL-10-1082 A/G were detected by polymerase chain reaction amplification-restriction fragment length polymorphism analysis.

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