Interleukin

Polymorphisms in promoter regions of IL-6 and IL-10 genes in breast cancer: a case-control study

E. S. AlSuhaibani, Kizilbash, N. A., Malik, S., Dasti, J. I., F. Beladi, A., El-Morshedi, N., AlSuhaibani, E. S., Kizilbash, N. A., Malik, S., Dasti, J. I., F. Beladi, A., El-Morshedi, N., AlSuhaibani, E. S., Kizilbash, N. A., Malik, S., Dasti, J. I., F. Beladi, A., and El-Morshedi, N., Polymorphisms in promoter regions of IL-6 and IL-10 genes in breast cancer: a case-control study, vol. 15, p. -, 2016.

Polymorphisms in interleukin genes (IL-6 and IL-10) are involved in the pathogenesis of breast cancer. This study investigated polymorphisms in the promoter regions of IL-6 (-174G/C) and IL-10 (-1082G/A) through a case-control study employing 80 female subjects who were pathologically diagnosed with breast cancer. All patients received follow-up care at the Mansoura University Hospital, Mansoura, Egypt. We included another 80 females (controls) from the same population, showing no signs of malignancy.

Correlation of CD4+ CD25+ Foxp3+ Treg with the recovery of joint function after total knee replacement in rats with osteoarthritis

S. - Y. Guo, Ding, Y. - J., Li, L., Zhang, T., Zhang, Z. - Z., and Zhang, E. - S., Correlation of CD4+ CD25+ Foxp3+ Treg with the recovery of joint function after total knee replacement in rats with osteoarthritis, vol. 14, pp. 7290-7296, 2015.

In this study, we observed changes in CD4+ CD25+ Foxp3+ Treg expression in rats with osteoarthritis (OA) to explore the role that CD4+ CD25+ Foxp3+ Treg plays in the decline in the condition of OA rats. Thirty rats were randomly divided into 2 groups equally and OA was induced in rats in the model group by injection of papain and l-cysteine into the right knee joint.

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