Intercellular adhesion molecule-1

Upregulation of ICAM-1 and IL-1β protein expression promotes lung injury in chronic obstructive pulmonary disease

Y. X. Wang, Ji, M. L., Jiang, C. Y., Qian, Z. B., Wang, Y. X., Ji, M. L., Jiang, C. Y., and Qian, Z. B., Upregulation of ICAM-1 and IL-1β protein expression promotes lung injury in chronic obstructive pulmonary disease, vol. 15, p. -, 2016.

Chronic obstructive pulmonary disease (COPD) is a devastating lung disorder characterized by sustained airway flow restriction that is not fully reversible. The precise pathogenic mechanisms are unknown, but it is clear that cigarette smoking and chronic inflammatory stimulation are the major causes of COPD. Lung inflammation associated with COPD involves multiple cytokines, aggregation, and activation of neutrophils in the airway and lung tissue, and release of proteases and oxygen free radicals.

Association of polymorphism in ICAM-1 (K469E) and cytology parameters in patients’ initial blood test with acute ischemic stroke

D. Wang, Zhang, F. H., Zhao, Y. T., Xiao, X. G., Liu, S., Shi, H. B., Lin, A. L., Wang, Y. J., Han, Q., and Sun, Q. M., Association of polymorphism in ICAM-1 (K469E) and cytology parameters in patients’ initial blood test with acute ischemic stroke, vol. 14, pp. 15520-15529, 2015.

Acute ischemic stroke (AIS) has become a serious health problem in many countries because of its poor outcome and worsening epidemic trend. Early identification of genetic risk factors and physiological indicators for stroke occurrence may help to reduce the incidence of stroke.

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