Integrin β1

Significance of the expression of integrin β1, VEGF and MVD in hypopharyngeal squamous cell carcinoma

Y. M. Hong, Gan, W. G., and Xu, Z. H., Significance of the expression of integrin β1, VEGF and MVD in hypopharyngeal squamous cell carcinoma, vol. 13, pp. 6455-6465, 2014.

This study aimed to determine the expression of integrin β1 and vascular endothelial growth factor (VEGF) and microvascular density (MVD) by CD105 staining in hypopharyngeal squamous cell carcinoma to determine their association with clinicopathologic characteristics, and to determine their role and the effects of their interactions in the development and progression of hypopharyngeal squamous cell carcinomas. The expression of integrin β1 and VEGF and MVD in hypopharyngeal squamous cell carcinomas and normal hypopharyngeal tissues were evaluated using immunohistochemistry.

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