Insulin-like growth factor II

Genetic polymorphisms of the IGF-II gene intron 8 coding region and its association with growth and carcass traits in yak

Y. F. Zeng, Ding, X. Z., Cheng, S. R., and Yu, S. J., Genetic polymorphisms of the IGF-II gene intron 8 coding region and its association with growth and carcass traits in yak, vol. 12, pp. 6602-6610, 2013.

Insulin-like growth factor II (IGF-II) plays a key role in mammalian growth and is involved in stimulating fetal cell division, differentiation, and metabolic regulation. IGF-II is considered a candidate gene for genetic markers of growth and carcass traits. Therefore, in this study, the associations of single nucleotide polymorphisms (SNPs) in the IGF-II gene region with growth and carcass characteristics in five yak breeds were investigated. Two SNPs, G330C and A358G, were identified by sequencing intron 8 of the IGF-II gene in homozygotes.

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