The insertion/deletion polymorphism (rs3783553 TTCA/-) in the 3' untranslated region of interleukin-1A (IL1A) has been studied intensively and has been shown to affect tumor risk. We studied the frequency of the IL1A gene polymorphism rs3783553 and evaluated its relationship with breast cancer (BC). A hospital-based case-control study comprising 228 patients with histologically confirmed BC and 241 healthy subjects was conducted. Polymerase chain reaction was used to detect the IL1A rs3783553 polymorphism.
“A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer”, vol. 15, p. -, 2016.,
“Screening of polymorphisms located in the FGF20 and TMEM175 genes in North Chinese Parkinson’s disease patients”, vol. 14, pp. 13679-13687, 2015.,
Genome-wide association studies have reported numerous susceptibility loci for Parkinson’s disease (PD). However, there have been few replication studies examining these loci in northern Chinese populations.