Insertion/deletion

A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer

X. Huang, Yang, Y., Cui, Z. W., Wang, J., Gao, L. B., Huang, X., Yang, Y., Cui, Z. W., Wang, J., and Gao, L. B., A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer, vol. 15, p. -, 2016.

The insertion/deletion polymorphism (rs3783553 TTCA/-) in the 3' untranslated region of interleukin-1A (IL1A) has been studied intensively and has been shown to affect tumor risk. We studied the frequency of the IL1A gene polymorphism rs3783553 and evaluated its relationship with breast cancer (BC). A hospital-based case-control study comprising 228 patients with histologically confirmed BC and 241 healthy subjects was conducted. Polymerase chain reaction was used to detect the IL1A rs3783553 polymorphism.

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