IL-10

Polymorphisms in promoter regions of IL-6 and IL-10 genes in breast cancer: a case-control study

E. S. AlSuhaibani, Kizilbash, N. A., Malik, S., Dasti, J. I., F. Beladi, A., El-Morshedi, N., AlSuhaibani, E. S., Kizilbash, N. A., Malik, S., Dasti, J. I., F. Beladi, A., El-Morshedi, N., AlSuhaibani, E. S., Kizilbash, N. A., Malik, S., Dasti, J. I., F. Beladi, A., and El-Morshedi, N., “Polymorphisms in promoter regions of IL-6 and IL-10 genes in breast cancer: a case-control study”, vol. 15, p. -, 2016.

Polymorphisms in interleukin genes (IL-6 and IL-10) are involved in the pathogenesis of breast cancer. This study investigated polymorphisms in the promoter regions of IL-6 (-174G/C) and IL-10 (-1082G/A) through a case-control study employing 80 female subjects who were pathologically diagnosed with breast cancer. All patients received follow-up care at the Mansoura University Hospital, Mansoura, Egypt. We included another 80 females (controls) from the same population, showing no signs of malignancy.

Role of IL-10 polymorphisms in susceptibility to hepatitis B virus-related hepatocellular carcinoma

M. W. Peng, Lu, S. Q., Liu, J., Dong, C. Y., Peng, M. W., Lu, S. Q., Liu, J., Dong, C. Y., Peng, M. W., Lu, S. Q., Liu, J., and Dong, C. Y., “Role of IL-10 polymorphisms in susceptibility to hepatitis B virus-related hepatocellular carcinoma”, vol. 15, p. -, 2016.

We conducted a case-control study to investigate the role of three common single nucleotide polymorphisms of IL-10 (-592G/A, -819T/C, and -1082A/C) in the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). The study included 173 HBV-related HCC patients and 182 healthy controls. A polymerase chain reaction-restriction fragment length polymorphism assay was applied to assess the sequence variants of interest.

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