ICAM-1

Effect of total peony glucoside pretreatment on NF-κB and ICAM-1 expression in myocardial tissue of rat with myocardial ischemia-reperfusion injury

L. Lu, Wei, P., Cao, Y., Zhang, Q., Liu, M., Liu, X. D., Wang, Z. L., Zhang, P. Y., Lu, L., Wei, P., Cao, Y., Zhang, Q., Liu, M., Liu, X. D., Wang, Z. L., and Zhang, P. Y., “Effect of total peony glucoside pretreatment on NF-κB and ICAM-1 expression in myocardial tissue of rat with myocardial ischemia-reperfusion injury”, vol. 15, no. 4, p. -, 2016.

INTRODUCTION

Fast, effective recovery of the coronary blood flow, after myocardial ischemia, is an effective method to treat this ischemia. However, myocardial ischemia-reperfusion (I/R) can aggravate ischemia-induced cardiac dysfunction and myocardial cell damage, leading to intracellular calcium overload, apoptosis, and inflammation. Therefore, clarifying its mechanism is important for the prevention of myocardial I/R injury.

Protective effect of quercetin on acute lung injury in rats with sepsis and its influence on ICAM-1 and MIP-2 expression

L. Meng, Lv, Z., Yu, Z. Z., Xu, D., Yan, X., Meng, L., Lv, Z., Yu, Z. Z., Xu, D., and Yan, X., “Protective effect of quercetin on acute lung injury in rats with sepsis and its influence on ICAM-1 and MIP-2 expression”, vol. 15, p. -, 2016.

This study aimed to explore the protective effect of quercetin on acute lung injury (ALI) in rats with sepsis and the related mechanism. Rats were administered different doses of quercetin intraperitoneally, and blood samples and lung tissue were collected at 24 h after treatment. Arterial blood gases, lung water content, protein content, and cell counts in bronchoalveolar lavage fluid (BALF) were measured. Morphological changes in lung tissue pathology were observed under a light microscope.

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