Hypoxia

Protective effects against and potential mechanisms underlying the effect of magnesium isoglycyrrhizinate in hypoxiareoxygenation injury in rat liver cells

J. Zheng, Wu, G., Hu, G. X., Peng, Y. Z., and Xiong, X. J., Protective effects against and potential mechanisms underlying the effect of magnesium isoglycyrrhizinate in hypoxiareoxygenation injury in rat liver cells, vol. 14, pp. 15453-15461, 2015.

We examined the protective effects of magnesium isoglycyrrhizinate (MgIG) on hypoxia-reoxygenation injury in rat liver cells. Rat liver cells in the logarithmic growth phase were divided into the hypoxia-reoxygenation injury model group and MgIG pretreatment group (0.01, 0.1, 1, 10, 100 mg/mL). After 24-h pretreatment, we detected the effects of MgIG on liver cell viability using the methyl thiazolyl tetrazolium (MTT) assay at 6-h hypoxia and 4-h reoxygenation.

Effect of chronic hypoxia on penile erectile function in rats

D. P. Yu, Liu, X. H., and Wei, A. Y., Effect of chronic hypoxia on penile erectile function in rats, vol. 14, pp. 10482-10489, 2015.

We examined the relationship between chronic hypoxia and erectile dysfunction in rat and its possible pathogenic mechanism. Forty-eight white male adult Sprague-Dawley rats were randomly divided into a test group and a control group. In accordance with the experimental time (2, 6, and 10 weeks), each group was divided into 3 subgroups, with 8 rats in each subgroup. Rats in the test group were fed in an airtight hypoxia cabin, while rats in the control group were maintained in a normal environment, with other conditions kept the same.

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