Hypovolemic shock

Effects of goal-directed fluid therapy with different lactated Ringer’s: hydroxyethyl starch ratios in hemorrhagic shock dogs

J. P. Tao, Huang, Q. Q., Huang, H. Q., Yang, J. J., Shi, M., Zhou, Y., Wan, L. J., Zhou, C., Ou, Y. J., Tong, Y. Y., Yang, D. G., and Si, Y. Y., Effects of goal-directed fluid therapy with different lactated Ringer’s: hydroxyethyl starch ratios in hemorrhagic shock dogs, vol. 14, pp. 6649-6663, 2015.

The effects of goal-directed fluid therapy, with lactated Ringer’s (LR) and 6% hydroxyethyl starch (HES) solution, on hemorrhagic shock dogs are unknown. We aimed to determine the optimal LR: HES ratio for the resuscitation of hemorrhagic shock dogs. Hemorrhagic shock was induced in 40 ventilated dogs by drawing an estimated 60% blood volume.

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