Hypertrophic scar

Acute toxic effects of sonodynamic therapy on hypertrophic scar fibroblasts of rabbit ears

W. Li, Fei, J. F., Yang, Q., Li, B. L., Lin, C., Yue, Q., and Meng, Q. G., Acute toxic effects of sonodynamic therapy on hypertrophic scar fibroblasts of rabbit ears, vol. 14, pp. 4203-4214, 2015.

The objective of this study was to observe the acute cytotoxic effects of hematoporphyrin monomethyl ether sonodynamic therapy (HMME-SDT) on hypertrophic scar fibroblasts of rabbit ears. We first assessed the effects of different irradiation times and HMME concentrations on the survival of hypertrophic scar fibroblasts using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay to determine the optimum irradiation time and HMME concentration.

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