Hyperthermophiles

Protein thermostability in Archaea and Eubacteria

S. Trivedi, Gehlot, H. S., and Rao, S. R., Protein thermostability in Archaea and Eubacteria, vol. 5. pp. 816-827, 2006.

In order to survive at high temperatures, thermophilic prokaryotes (Archaea and Eubacteria) adopt different strategies. Among several important contributing factors for stability of proteins are CG-rich codons, the ratio of charged amino acids compared to uncharged amino acids, ionic interactions, amino acid preferences and their distribution, post-translational modifications, and solute accumulation. However, these factors may differ from taxon to taxon, both within and between species depending upon the composition of proteins found in these organisms.

Comparison of simple sequence repeats in 19 Archaea

S. Trivedi, Comparison of simple sequence repeats in 19 Archaea, vol. 5, pp. 741-772, 2006.

All organisms that have been studied until now have been found to have differential distribution of simple sequence repeats (SSRs), with more SSRs in intergenic than in coding sequences. SSR distribution was investigated in Archaea genomes where complete chromosome sequences of 19 Archaea were analyzed with the program SPUTNIK to find di- to penta-nucleotide repeats. The number of repeats was determined for the complete chromosome sequences and for the coding and non-coding sequences.

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