Host-pathogen interaction

Virulence insights from the Paracoccidioides brasiliensis transcriptome

A. Henrique Tavares, Silva, S. Souza, Bernardes, V. Vilmar, Maranhão, A. Queiróz, Maranhão, A. Queiróz, Kyaw, C. Maria Kyaw, Poças-Fonseca, M., and Silva-Pereira, I., Virulence insights from the Paracoccidioides brasiliensis transcriptome, vol. 4. pp. 372-389, 2005.

Paracoccidioides brasiliensis, the etiologic agent of paracoccidioidomycosis, is a dimorphic fungus, which is found as mycelia at 22-26ºC and as yeasts at 37ºC. A remarkable feature common to several pathogenic fungi is their ability to differentiate from mycelium to yeast morphologies, or vice-versa. Although P. brasiliensis is a recognized pathogen for humans, little is known about its virulence genes. In this sense, we performed a search for putative virulence genes in the P. brasiliensis transcriptome.

Subscribe to Host-pathogen interaction