HMGB3

HMGB3 characterization in gastric cancer

Y. Gong, Cao, Y., Song, L., Zhou, J., Wang, C., and Wu, B., HMGB3 characterization in gastric cancer, vol. 12, pp. 6032-6039, 2013.

Gastric cancer is a major health problem worldwide; it is the second most common cause of cancer death in the world. Recent studies indicate that the high-mobility group (HMG) of chromosomal proteins is associated with cancer progression. However, HMGB3 has been little studied. We analyzed the co-expression network between HMGB3 and differentially-expressed genes in the GSE17187 database, identifying the relevant transcription factors, and the conserved domain of HMGB3 to understand the underlying regulation mechanisms involved in gastric cancer.

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