Cytotoxicity of 1-dodecyl-3-methylimidazolium bromide on HepG2 cells
“Cytotoxicity of 1-dodecyl-3-methylimidazolium bromide on HepG2 cells”, vol. 14, pp. 13342-13348, 2015.
, We evaluated the cytotoxicity of 1-dodecyl-3-methylimidazolium bromide ([C12mim][Br]) on HepG2 cells and its influence on plasma membrane permeability. The results showed that [C12mim][Br] inhibited HepG2 cell growth and decreased cell viability in a concentration-dependent manner. The results also revealed that [C12mim][Br] exposure induced apoptosis in [C12mim][Br]-treated HepG2 cells. In addition, the results showed that [C12mim][Br] increased membrane permeability in HepG2 cells.