HepG2 cells

Cytotoxicity of 1-dodecyl-3-methylimidazolium bromide on HepG2 cells

T. H. Li, Jing, C. Q., Gao, K. L., Yue, W. Y., and Li, S. F., Cytotoxicity of 1-dodecyl-3-methylimidazolium bromide on HepG2 cells, vol. 14, pp. 13342-13348, 2015.

We evaluated the cytotoxicity of 1-dodecyl-3-methylimidazo­lium bromide ([C12mim][Br]) on HepG2 cells and its influence on plasma membrane permeability. The results showed that [C12mim][Br] inhibited HepG2 cell growth and decreased cell viability in a concentration-depen­dent manner. The results also revealed that [C12mim][Br] exposure induced apoptosis in [C12mim][Br]-treated HepG2 cells. In addition, the results showed that [C12mim][Br] increased membrane permeability in HepG2 cells.

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