Hepatocyte growth

Three branches of phospholipase C signaling pathway promote hepatocyte growth in rat liver regeneration

G. G. Xu, Geng, Z., Zhou, X. C., He, Y. G., He, T. T., Mei, J. X., Yang, Y. J., Liu, Y. Q., and Xu, C. S., Three branches of phospholipase C signaling pathway promote hepatocyte growth in rat liver regeneration, vol. 14, pp. 5710-5723, 2015.

In general, the phospholipase C (PLC) signaling pathway is involved in many physiological activities, including cell growth. However, little is known regarding how the PLC signaling pathway participates in regulating hepatocyte (HC) growth during liver regeneration (LR). To further explore the influence of the PLC signaling pathway on HCs at the cellular level, HCs of high purity and vitality were isolated using Percoll density-gradient centrifugation after partial hepatectomy.

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