Hepatocellular carcinoma

Effect of ST2825 on the proliferation and apoptosis of human hepatocellular carcinoma cells

Y. Deng, Sun, J., Zhang, L. D., Deng, Y., Sun, J., and Zhang, L. D., “Effect of ST2825 on the proliferation and apoptosis of human hepatocellular carcinoma cells”, vol. 15, p. -, 2016.

The purpose of this study was to investigate the effect of ST2825, an inhibitor of myeloid differentiation factor 88 (MyD88), on the proliferation and apoptosis of human hepatocellular carcinoma (HCC) cells as well as the potential mechanism and clinical significance of ST2825 in the treatment of HCC. Immunohistochemical staining with an MyD88 antibody was performed on tissues from 80 human HCC patients and adjacent normal tissues.

Role of IL-10 polymorphisms in susceptibility to hepatitis B virus-related hepatocellular carcinoma

M. W. Peng, Lu, S. Q., Liu, J., Dong, C. Y., Peng, M. W., Lu, S. Q., Liu, J., Dong, C. Y., Peng, M. W., Lu, S. Q., Liu, J., and Dong, C. Y., “Role of IL-10 polymorphisms in susceptibility to hepatitis B virus-related hepatocellular carcinoma”, vol. 15, p. -, 2016.

We conducted a case-control study to investigate the role of three common single nucleotide polymorphisms of IL-10 (-592G/A, -819T/C, and -1082A/C) in the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). The study included 173 HBV-related HCC patients and 182 healthy controls. A polymerase chain reaction-restriction fragment length polymorphism assay was applied to assess the sequence variants of interest.

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