Hepatitis B

Reduced cortisol in the absence of bacterial infection in patients with hepatitis B virus cirrhosis

J. Zhang, Yu, H. - W., Li, J., Zhu, Y. - K., Wang, K. - F., Jia, L., and Meng, Q. - H., Reduced cortisol in the absence of bacterial infection in patients with hepatitis B virus cirrhosis, vol. 14, pp. 7957-7963, 2015.

In liver cirrhosis with bacterial infection, hepatoadrenal syndrome has been described recently as a progressive impairment in the adrenocortical reserve, with deficient production or action of glucocorticoids resulting in adrenal insufficiency. The aim of this study was to explore the characteristics of cortisol in hepatitis B virus (HBV) cirrhosis patients in the absence of bacterial infection.

Functional polymorphisms in microRNA gene and hepatitis B risk among Asian population: a meta-analysis

G. Q. Zhou, Meng, H., Wang, J. R., Sun, F. X., Wang, X. J., Wang, R. B., and Wang, X. B., Functional polymorphisms in microRNA gene and hepatitis B risk among Asian population: a meta-analysis, vol. 14, pp. 4767-4777, 2015.

Genetic mutations in microRNA gene can alter expression, which may interact to increase the risk of developing various diseases, including hepatitis B. However, published results are inconclusive or ambiguous. The aim of this review and meta-analysis is to more precisely estimate the association between polymorphisms in microRNA genes and hepatitis B risk. A digital search was performed of the MEDLINE EMBASE, CNKI, and CBM databases to identify relevant articles published up to February 18, 2014.

Immunomodulatory effect of bone marrow mesenchymal stem cells on T lymphocytes in patients with decompensated liver cirrhosis

C. H. Guo, Han, L. X., Wan, M. R., Deng, G. J., and Gan, J. H., Immunomodulatory effect of bone marrow mesenchymal stem cells on T lymphocytes in patients with decompensated liver cirrhosis, vol. 14, pp. 7039-7046, 2015.

We explored the immunomodulatory effects of bone marrow mesenchymal stem cells (BMSCs) on peripheral blood T lym­phocytes in patients with decompensation stage, hepatitis B-associated cirrhosis. MSCs from nine patients were analyzed by flow cytometry. Peripheral blood lymphocytes were isolated for fluorescent staining.

Curative effect of combined lamivudine, adefovir dipivoxil, and stem cell transplantation on decompensated hepatitis B cirrhosis

L. Liu, Yan, Y., Zhou, J., Huang, L. W., He, C. P., Ling, K., Zhou, H. C., Wen, Q. M., and Wang, X. M., Curative effect of combined lamivudine, adefovir dipivoxil, and stem cell transplantation on decompensated hepatitis B cirrhosis, vol. 13, pp. 9336-9342, 2014.

This study assessed the clinical efficacy of lamivudine and adefovir dipivoxil combined with autologous bone marrow stem cell transplantation as treatment for patients with hepatitis B and decompensated liver cirrhosis. In total, 77 patients with hepatitis B and decompensated liver cirrhosis were randomly divided into two groups.

Evaluation of a histocompatibility antigen related to hepatitis B virus in patients with hepatocellular carcinoma in the western Brazilian Amazon

S. R. S. Chalub, da Silva, R. M., da Silva, A. P. S., de Aquino, P. F., Sadahiro, A., and Kalil, A. N., Evaluation of a histocompatibility antigen related to hepatitis B virus in patients with hepatocellular carcinoma in the western Brazilian Amazon, vol. 12, pp. 1336-1346, 2013.

Hepatocellular carcinoma is an infection of variable incidence that can be caused by hepatitis B virus (HBV), which is endemic in the Amazon region. The diagnosis of HBV can be performed through the use of serum markers such as the hepatitis B surface antigen. The chronic HBV can cause mutagenesis and carcinogenesis, being the susceptibility of infection due to allele human leukocyte antigen (HLA).

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