Hepatic cirrhosis

Expression of toll-like receptors in hepatic cirrhosis and hepatocellular carcinoma

L. Sun, Dai, J. J., Hu, W. F., Wang, J., Sun, L., Dai, J. J., Hu, W. F., and Wang, J., Expression of toll-like receptors in hepatic cirrhosis and hepatocellular carcinoma, vol. 15, p. -, 2016.

Toll-like receptors (TLRs) can specifically identify pathogen-associated molecular patterns (PAMPs) by recognizing structural patterns in diverse microbial molecules, and can provide an effective defense against multiple microbial infectious. A variety of TLRs can be expressed on the surface of liver parenchymal as well as nonparenchymal cells. Kupffer cells are a type of hepatic nonparenchymal macrophage, and are positively associated with the severity of liver fibrosis.

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