Helicobacter pylori

Expression of macrophage migration-inhibitory factor in duodenal ulcer and its relation to Helicobacter pylori infection

X. H. Yu, Zhang, Q., Yang, X. P., Yang, W., Dai, F., Qian, Z., Wang, Z. L., Wu, C. F., Zhao, H. Z., and Wang, G. H., Expression of macrophage migration-inhibitory factor in duodenal ulcer and its relation to Helicobacter pylori infection, vol. 14, pp. 13860-13867, 2015.

The aim of this study was to examine the expression of macrophage migration-inhibitory factor (MIF) in duodenal ulcer epithelial cells and its relation to Helicobacter pylori (Hp) infection, and to discuss the pathogenic roles of MIF expression and Hp infection in duodenal ulcer. MIF protein and mRNA expression was examined in samples from patients with duodenal ulcer with and without Hp infection (N = 40 each, experimental group), and in normal duodenal bulb mucosal tissue (N = 40, control group) using immunohistochemistry and in situ hybridization.

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