Haplotype

Haplotypes of qGL3 and their roles in grain size regulation with GS3 alleles in rice

Y. D. Zhang, Zhu, Z., Zhao, Q. Y., Chen, T., Yao, S., Zhou, L. H., Zhao, L., Zhao, C. F., Wang, C. L., Zhang, Y. D., Zhu, Z., Zhao, Q. Y., Chen, T., Yao, S., Zhou, L. H., Zhao, L., Zhao, C. F., Wang, C. L., Zhang, Y. D., Zhu, Z., Zhao, Q. Y., Chen, T., Yao, S., Zhou, L. H., Zhao, L., Zhao, C. F., and Wang, C. L., Haplotypes of qGL3 and their roles in grain size regulation with GS3 alleles in rice, vol. 15, p. -, 2016.

Grain size is an important trait that directly influences rice yield. The qGL3 and GS3 genes are two putative regulators that play a role in grain size determination. A single rare nucleotide substitution (C→A) at position 1092 in exon 10 of qGL3 might be responsible for variations in grain size. However, little is known about the haplotype variations of qGL3 and their interactions with GS3 during the regulation of grain length and grain weight.

Relationship between polymorphisms in the proline dehydrogenase gene and schizophrenia risk

F. Ghasemvand, Omidinia, E., Salehi, Z., and Rahmanzadeh, S., Relationship between polymorphisms in the proline dehydrogenase gene and schizophrenia risk, vol. 14, pp. 11681-11691, 2015.

Previous studies have suggested that an association exists between the proline dehydrogenase gene (PRODH) and increased schizophrenia risk. We examined the prevalence of the PRODH 757C/T (Arg185Trp), 1766A/G (Gly521Arg), and 1852G/A (intronic mutation) polymorphisms in 175 patients with schizophrenia and 185 control subjects. All subjects were of Iranian ancestry. The PRODH 757TT, 1852AA, and 1766GG genotypes were associated with an increased risk of schizophrenia (odds ratio = 1.38, 95% confidence interval: 0.88-2.16, P = 0.001, P = 0.001, respectively).

Linkage analysis of SNPs in IGFBP-6 and its relation with the body sizes of pig

X. B. Fang, Liu, S. C., Wu, Q. Y., Li, S. M., Cheng, Y. Y., Fu, H. Y., Lu, C., Su, D., Yu, H., and Hao, L. L., Linkage analysis of SNPs in IGFBP-6 and its relation with the body sizes of pig, vol. 14, pp. 17273-17280, 2015.

Insulin-like growth factor binding protein-6 (IGFBP-6) is a member of the IGFBP family, which is known to be a key factor in regulating the effect of insulin-like growth factor-2 (IGF-2) on the animal growth and development. Gene sequences of 3'-untranslated regions (UTR) and exon 4 of IGFBP-6 may influence the expression and proteolysis of IGFBP-6.

Association of NPRA and NPRC gene variants and hypertension in Mongolian population

P. Y. Chang, Liu, Z. Y., Qin, L., and Zhao, P., Association of NPRA and NPRC gene variants and hypertension in Mongolian population, vol. 14, pp. 18494-18502, 2015.

NPRA and NPRC are candidate susceptibility genes for essential hypertension (EH) and play a key role in the regulation of plasma levels and biological effects of natriuretic peptides. The aims of the present study were to find new genetic markers in the NPRA and NPRC genes and to assess relationships between variants and EH. A total of 797 unrelated Mongolian herdsmen were enrolled, including 389 EH patients and 408 normotensive controls. Genotyping was performed using the polymerase chain reaction/ligase detection reaction assay.

Association of SNPs in the PPARγ gene and hypertension in a Mongolian population

L. Yang, Tian, R. G., Chang, P. Y., Yan, M. R., and Su, X. L., Association of SNPs in the PPARγ gene and hypertension in a Mongolian population, vol. 14, pp. 19295-19308, 2015.

The association of single nucleotide polymorphisms (SNPs) in PPARγ with hypertension is controversial. The aim of the present study was to clarify the contributions of PPARγ genetic variants to hypertension through an association study. A total of 414 unrelated Mongolian herdsmen and 524 Han farmers were included in this study. Fourteen intronic SNPs were analyzed and genotyped using a polymerase chain reaction/ligase detection reaction assay.

Association of variants in renal salt reabsorption-related gene SLC12A3 with essential hypertension in a Mongolian population

J. Q. Liang, Xi, Y. G., An, C. Y., and Su, X. L., Association of variants in renal salt reabsorption-related gene SLC12A3 with essential hypertension in a Mongolian population, vol. 14, pp. 10026-10036, 2015.

Mounting evidence has implicated the SLC12A3 gene in essential hypertension. Here, we examined the potential associations of common variants of the SLC12A3 gene with blood pressure traits in Mongolians in China. Genomic DNA was extracted from 508 unrelated Mongolian patients with essential hypertension and 246 normotensive Mongolian subjects for genotyping. The genotype distributions of all selected polymorphisms were consistent with Hardy-Weinberg equilibrium.

Phylogeography of pink pineapple mealybugs, Dysmicoccus brevipes (Cockerell) reveals the history of pineapple introduction and cultivation in China

Y. B. He, Zhan, R. L., Sun, G. M., Wu, J. B., and Zhao, Y. L., Phylogeography of pink pineapple mealybugs, Dysmicoccus brevipes (Cockerell) reveals the history of pineapple introduction and cultivation in China, vol. 14, pp. 9890-9897, 2015.

The pink pineapple mealybug (PPM), Dysmicoccus brevipes (Cockerell) (Hemiptera: Pseudococcidae), is a widespread plant-sucking insect of considerable concern because it transmits the pineapple mealybug wilt-associated virus. Its distribution is closely linked with its host, the pineapple [Ananas comosus (L.) Merrill] because of its wingless and parthenogenetic characteristics. To investigate the history of D. brevipes introduction and the cultivation of pineapple in China, samples of D.

Genome-wide association study of meat quality traits in chicken

T. Zhang, Fan, Q. C., Wang, J. Y., Zhang, G. X., Gu, Y. P., and Tang, Y., Genome-wide association study of meat quality traits in chicken, vol. 14, pp. 10452-10460, 2015.

Meat quality traits are very important in the poultry industry. To identify single nucleotide polymorphisms (SNPs) and candidate genes affecting meat quality traits, a genome-wide association study was performed using the Illumina chicken 60K SNP beadchip in Jinghai yellow chicken. Four meat quality traits were measured. Two SNPs reached 5% Bonferroni genome-wide significance (P < 1.8E-6) and 7 SNPs reached “suggestive” genome-wide significance (P < 3.59E-6) with meat quality.

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