GWAS

Genome wide association study on early puberty in Bos indicus

A. V. Nascimento, Matos, M. C., Seno, L. O., Romero, A. R. S., Garcia, J. F., Grisolia, A. B., Nascimento, A. V., Matos, M. C., Seno, L. O., Romero, A. R. S., Garcia, J. F., and Grisolia, A. B., Genome wide association study on early puberty in Bos indicus, vol. 15, p. -, 2016.

The aim of this study was to evaluate a genome wide association study (GWAS) approach to identify single nucleotide polymorphisms (SNPs) associated with fertility traits (early puberty) in Nellore cattle (Bos indicus). Fifty-five Nellore cows were selected from a herd monitored for early puberty onset (positive pregnancy at 18 months of age). Extremes of this phenotype were selected; 30 and 25 individuals were pregnant and non-pregnant, respectively, at that age. DNA samples were genotyped using a high-density SNP chip (>777.000 SNP).

A genome-wide association study of growth trait-related single nucleotide polymorphisms in Chinese Yancheng chickens

C. F. Jin, Chen, Y. J., Yang, Z. Q., Shi, K., and Chen, C. K., A genome-wide association study of growth trait-related single nucleotide polymorphisms in Chinese Yancheng chickens, vol. 14, pp. 15783-15792, 2015.

Chicken (Gallus gallus) growth traits are important economic traits, and many studies have been conducted on genetic selection for body weight. However, most of these studies have detected functional chromosome mutations or regions by conventional molecular markers or gene chips. In this study, we performed a new genome-wide association study using specific-locus amplified fragment sequencing (SLAF-seq) technology in purebred Yancheng chickens.

Single nucleotide polymorphisms associated with growth traits in Jinghai yellow chickens

M. A. Abdalhag, Zhang, T., Fan, Q. C., Zhang, X. Q., Zhang, G. X., Wang, J. Y., Wei, Y., and Wang, Y. J., Single nucleotide polymorphisms associated with growth traits in Jinghai yellow chickens, vol. 14, pp. 16169-16177, 2015.

Body weight is one of the most important economic traits in the poultry industry. In the present study, a custom SNP Beadchip was used to analyze the association between those 15 SNPs and 12 growth traits of Jinghai yellow chickens, and other important genetic parameters were also calculated and analyzed. The results indicated that nine of the 15 SNPs were associated with growth traits in Jinghai yellow chickens (P

Correlation between natriuretic peptide receptor C (NPR3) gene polymorphisms and hypertension in the Dai people of China

H. Sun, Yang, Z. Q., Liu, S. Y., Yu, L., Huang, K., Lin, K. Q., Chu, J. Y., and Huang, X. Q., Correlation between natriuretic peptide receptor C (NPR3) gene polymorphisms and hypertension in the Dai people of China, vol. 14, pp. 8786-8795, 2015.

Hypertension affects one-fifth of the world population. Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) that correlated with hyper­tension in large samples. However, the genetic mutations leading to hypertension might differ among various populations, as they have dif­ferent origins and are subjected to different environmental pressures. Therefore, additional studies are urgently needed to verify the GWAS findings across different populations.

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