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Association of glutathione S-transferase (GST) genetic polymorphisms with treatment outcome of cisplatin-based chemotherapy for advanced non-small cell lung cancer in a Chinese population

H. L. Xiao, Yang, Z. T., Han, F., Wei, H. X., Xiao, H. L., Yang, Z. T., Han, F., Wei, H. X., Xiao, H. L., Yang, Z. T., Han, F., and Wei, H. X., “Association of glutathione S-transferase (GST) genetic polymorphisms with treatment outcome of cisplatin-based chemotherapy for advanced non-small cell lung cancer in a Chinese population”, vol. 15, p. -, 2016.

The aim of this study was to evaluate the association of GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms with the chemotherapy response and overall survival of advanced NSCLC. Two hundred and sixty-two patients with histologically confirmed advanced NSCLC (inoperable TNM stages IIIA, IIIB, and IV) were enrolled to this hospital-based study between May 2009 and May 2012.

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Genet. Mol. Res.
ISSN 16765680

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