GSTM1

GSTM1/GSTT1-null genotyping role in leukemia development in Brazilian patients

D. K. Wosniaki, Marin, A. M., Soares, G. S., Zanette, D. L., Blanes, L., Munhoz, E. C., and Aoki, M., “GSTM1/GSTT1-null genotyping role in leukemia development in Brazilian patients”, Genetics and Molecular Research, vol. 21, no. 1, 2022.

Evidence of association of glutathione-S-transferase GSTT1 and GSTM1 null genotypes with susceptibility to oral cancer based on meta-analysis

A. K. Lopes, Tacca, A. L. M., Nogueira, N. A., Sodario, J. A., Vilanova-Costa, C. A. S. T., Saddi, V. A., Filho, A. Vde Moraes, and Silva, A. M. T. C., “Evidence of association of glutathione-S-transferase GSTT1 and GSTM1 null genotypes with susceptibility to oral cancer based on meta-analysis”, Genetics and Molecular Research, vol. 19, no. 4, 2020.

Association study between GSTM1 and GSTT1 genotypes and other possible risk factors in prostate cancer patients in a population from southwest Bahia, Brazil

L. C. F. de Souza, Brito, T. L. S., Almeida, A. T., Muniz, Y. P., Nishiyama, P. B., Souza, C. L., and Tomazi, L., “Association study between GSTM1 and GSTT1 genotypes and other possible risk factors in prostate cancer patients in a population from southwest Bahia, Brazil”, Genetics and Molecular Research, vol. 18, no. 3, 2019.

GSTT1 null genotype in sickle cell anemia and blood transfusion recurrence – a case report

O. S. Dias Neto, Silva, K. S. Fe, Barbosa, A. M., Rodrigues, D. A., Lagares, M. H., da Costa, I. R., and Moura, K. K. V. O., “GSTT1 null genotype in sickle cell anemia and blood transfusion recurrence – a case report”, Genetics and Molecular Research, vol. 18, no. 2, 2019.

Polymorphisms of the genes eNOS, GSTT1 and GSTM1 are significantly associated with atherosclerotic disease in hypertensive patients

M. P. Moraes, Silva, K. S. Fe, Lagares, M. H., Barbosa, A. M., Martins, J. V. M., Campedelli, F. L., da Costa, I. R., Rodrigues, D. A., and Moura, K. K. V. O., “Polymorphisms of the genes eNOS, GSTT1 and GSTM1 are significantly associated with atherosclerotic disease in hypertensive patients”, Genetics and Molecular Research, vol. 18, no. 1, 2019.

Null polymorphisms in GSTT1 and GSTM1 genes and their associations with smoking and cervical cancer

A. L. M. Tacca, Lopes, A. K., Vilanova-Costa, C. A. S. T., Silva, A. M. T. C., Costa, S. H. N., Nogueira, N. A., Ramos, J. E. P., Ribeiro, A. A., and Saddi, V. A., “Null polymorphisms in GSTT1 and GSTM1 genes and their associations with smoking and cervical cancer”, Genetics and Molecular Research, vol. 18, no. 1, 2019.

GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population

M. N. Khabaz, Nedjadi, T., Gari, M. A., Al-Maghrabi, J. A., Atta, H. M., Bakarman, M., Gazzaz, Z. J., Khabaz, M. N., Nedjadi, T., Gari, M. A., Al-Maghrabi, J. A., Atta, H. M., Bakarman, M., Gazzaz, Z. J., Khabaz, M. N., Nedjadi, T., Gari, M. A., Al-Maghrabi, J. A., Atta, H. M., Bakarman, M., and Gazzaz, Z. J., “GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population”, vol. 15, p. -, 2016.

The enzyme glutathione S-transferase Mu 1 (GSTM1) is encoded by the GSTM1 gene. Polymorphisms in GSTM1 affect the detoxifying function of the enzyme variants. This forms the basis of the debate about the impact of the GSTM1 null/present genotype on colorectal carcinoma risk. We tested the potential influence of GSTM1 polymorphisms on the development of colorectal cancer.

Effect of CYP1A1 and GSTM1 genetic polymorphisms on bone tumor susceptibility

L. Li, Li, J. G., Liu, C. Y., and Ding, Y. J., “Effect of CYP1A1 and GSTM1 genetic polymorphisms on bone tumor susceptibility”, vol. 14, pp. 16600-16607, 2015.

Tumor gene polymorphisms are often associated with individual susceptibility to genetic diseases. Cytochrome P4501A1 (CYP1A1) and glutathione S-transferase mu 1 (GSTM1) gene polymorphisms are closely related to the susceptibility of the body to chemical carcinogens in the environment. Therefore, we explored the relationship between CYP1A1 and GSTM1 gene polymorphisms and susceptibility to bone tumors.

Glutathione S-transferase polymorphisms in varicocele patients: a meta-analysis

B. Zhu, Yin, L., and Zhang, J. Y., “Glutathione S-transferase polymorphisms in varicocele patients: a meta-analysis”, vol. 14, pp. 18851-18858, 2015.

The glutathione S-transferase (GST) family represents a major group of detoxification and antioxidant enzymes. Studies have shown that high oxidative stress levels are associated with varicocele. The objective of this study was to assess the relationship between GSTM1 and GSTT1 null polymorphisms and varicocele using a study group of 497 varicocele patients and 476 control subjects. A systematic literature search (for articles published up to September 2014) utilizing Google Scholar and PubMed was conducted.