Glutathione transferase

Molecular analysis of the GSTT1 gene polymorphism in patients with clinical manifestation of atherosclerosis.

J. V. M. Martins, Rodrigues, D. A., Silva, K. S. F., Costa, I. R., Lagares, M. H., Campedelli, F. L., Barbosa, A. M., Morais, M. P., and Moura, K. K. V. O., “Molecular analysis of the GSTT1 gene polymorphism in patients with clinical manifestation of atherosclerosis.”, Genet Mol Res, vol. 16, no. 3, 2017.

Association between GSTM1, GSTT1, and GSTP1 polymorphisms and gastric cancer risk, and their interactions with environmental factors.

Z. H. Chen, Xian, J. F., and Luo, L. P., “Association between GSTM1, GSTT1, and GSTP1 polymorphisms and gastric cancer risk, and their interactions with environmental factors.”, Genet Mol Res, vol. 16, no. 1, 2017.

Association between CYP19A1, GSTM1, GSTT1, and GSTP1 genetic polymorphisms and the development of endometriosis in a Chinese population.

Y. Tuo, He, J. Y., Yan, W. J., and Yang, J., “Association between CYP19A1, GSTM1, GSTT1, and GSTP1 genetic polymorphisms and the development of endometriosis in a Chinese population.”, Genet Mol Res, vol. 15, no. 4, 2016.

 GSTT1, GSTM1, and GSTP1 polymorphisms as a prognostic factor in women with breast cancer

A. L. Oliveira, Rodrigues, F. F. Oliveira, Santos, R. Edos, Rozenowicz, R. L., and M. de Melo, B., “ GSTT1, GSTM1, and GSTP1 polymorphisms as a prognostic factor in women with breast cancer”, vol. 13, pp. 2521-2530, 2014.

The glutathione S-transferase (GST) family comprises phase-II cellular detoxification enzymes that catalyze the conjugation of chemotherapy drugs to glutathione and act on the apoptotic pathway.

GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer

A. L. Oliveira, Rodrigues, F. F. O., Santos, R. E., Aoki, T., Rocha, M. N., Longui, C. A., and Melo, M. B., “GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer”, vol. 9, pp. 1045-1053, 2010.

The glutathione S-transferase (GST) family consists of phase II detoxification enzymes that catalyze the conjugation of toxic substances, such as chemotherapeutic agents, to glutathione. We examined whether GSTT1/GSTT1“null”, GSTM1/GSTM1“null” and GSTP1Ile105Ile/GSTP1Ile105Val polymorphisms are associated with different response rates to neoadjuvant chemotherapy in the treatment of stage II and III breast cancer.

Subscribe to Glutathione transferase