Glutathione S-transferase theta 1

Polymorphisms of GSTM1, GSTT1, and p53 in Goiânia, Goiás

D. A. Rodrigues, Costa, I. R., Martins, J. V. M., Silva, K. S. Fe, and Moura, K. K. V. O., Polymorphisms of GSTM1, GSTT1, and p53 in Goiânia, Goiás, vol. 14, pp. 17358-17365, 2015.

Genetic polymorphisms are defined as changes within the DNA sequences of genes that have frequencies in the population higher than 1%. The glutathione S-transferases play an important role in the cellular detoxification systems involved in oxidative stress that can lead to accumulation of reactive oxygen species. Epidemiological studies have suggested that individuals with homozygous deletion of glutathione S-transferase mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1) are at higher risk of developing several types of neoplasias.

Subscribe to Glutathione S-transferase theta 1