Glucose

High levels of glucose promote the activation of hepatic stellate cells via the p38-mitogen-activated protein kinase signal pathway

L. K. Wu, Liu, Y. C., Ma, G., Shi, L. L., He, X. M., Wu, L. K., Liu, Y. C., Ma, G., Shi, L. L., and He, X. M., High levels of glucose promote the activation of hepatic stellate cells via the p38-mitogen-activated protein kinase signal pathway, vol. 15, p. -, 2016.

The relationship between the p38-mitogen-activated protein kinase (p38-MAPK) signal pathway and high glucose-induced hepatic stellate cell (HSC) activation was investigated in this study. Sixty human HSC samples were randomly selected and used in the control (cultured normally), high-glucose (cultured in the presence of high glucose), and blocking (cultured under high-glucose conditions in the presence of the p38-MAPK inhibitor, SB203580) groups.

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