Ginkgolide B

Alleviation of spinal cord injury by Ginkgolide B via the inhibition of STAT1 expression

J. L. Zheng, Li, B. S., Cao, X. C., Zhuo, W. K., Zhang, G., Zheng, J. L., Li, B. S., Cao, X. C., Zhuo, W. K., and Zhang, G., Alleviation of spinal cord injury by Ginkgolide B via the inhibition of STAT1 expression, vol. 15, p. -, 2016.

Ginkgolide B has been known to inhibit cell apoptosis by modulating multiple cytokines and plays an important role in neuroprotection. Signal transducer and activator of transcription 1 (STAT1) has been studied in a spinal cord injury (SCI) model. However, the role of Ginkgolide B in SCI treatment remains unclear. This study investigated the potential mechanism of Ginkgolide B using an SCI rat model. SD rats were used to generate an SCI model followed by Ginkgolide B injection (4 mg/kg) for 14 days.

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