Giemsa banding (GTG banding)

Balanced reciprocal translocation at amniocentesis: cytogenetic detection and implications for genetic counseling

H. G. Zhang, Zhang, X. Y., Zhang, H. Y., Tian, T., Xu, S. B., Liu, R. Z., Zhang, H. G., Zhang, X. Y., Zhang, H. Y., Tian, T., Xu, S. B., and Liu, R. Z., Balanced reciprocal translocation at amniocentesis: cytogenetic detection and implications for genetic counseling, vol. 15, p. -, 2016.

Balanced translocation is a common structural chromosomal rearrangement in humans. Carriers can be phenotypically normal but have an increased risk of pregnancy loss, fetal death, and the transmission of chromosomal abnormalities to their offspring. Existing prenatal screening technologies and diagnostic procedures fail to detect balanced translocation, so genetic counseling for carriers remains a challenge. Here, we report the characteristics of chromosomal reciprocal translocation in 3807 amniocentesis cases.

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