Genotoxic agents

Mitotic crossing-over induced by two commercial herbicides in diploid strains of the fungus Aspergillus nidulans

R. A. Cardoso, Pires, L. T. A., Zucchi, T. D., Zucchi, F. D., and Zucchi, T. M. A. D., Mitotic crossing-over induced by two commercial herbicides in diploid strains of the fungus Aspergillus nidulans, vol. 9, pp. 231-238, 2010.

Some herbicides are suspected of promoting teratogenic, carcinogenic and mutagenic events. Detection of induced mitotic crossing-over has proven to be an indirect way of testing the carcinogenic properties of suspicious substances, because mitotic crossing-over is involved in the multistep process of carcinogenesis. We examined mitotic crossing-over induced by two commercial herbicides (diuron and trifluralin) in diploid strains of Aspergillus nidulans based on the homozygotization index.

Cytogenetic damage in the buccal epithelium of Brazilian aviators occupationally exposed to agrochemicals

L. B. Minasi, Costa, E. O. A., Silva, D. M., Melo, C. O. A., de Almeida, J. G., Vieira, T. C., Júnior, R. L. Silva, Ribeiro, C. L., da Silva, C. C., and da Cruz, A. D., Cytogenetic damage in the buccal epithelium of Brazilian aviators occupationally exposed to agrochemicals, vol. 10. pp. 3924-3929, 2011.

The frequency of micronuclei in both buccal cells and peripheral blood lymphocytes is extensively used as a biomarker of chromosomal damage and genome stability in human populations. We examined whether prolonged exposure to complex mixtures of pesticides leads to an increase in cytogenetic damage.

Subscribe to Genotoxic agents