Genome

SNP detection using RNA-sequences of candidate genes associated with puberty in cattle.

M. M. Dias, Cánovas, A., Mantilla-Rojas, C., Riley, D. G., Luna-Nevarez, P., Coleman, S. J., Speidel, S. E., Enns, R. M., Islas-Trejo, A., Medrano, J. F., Moore, S. S., Fortes, M. R. S., Nguyen, L. T., Venus, B., Diaz, I. S. D. P., Souza, F. R. P., Fonseca, L. F. S., Baldi, F., Albuquerque, L. G., Thomas, M. G., and Oliveira, H. N., “SNP detection using RNA-sequences of candidate genes associated with puberty in cattle.”, Genet Mol Res, vol. 16, no. 1, 2017.

Genome-scale meta-analysis of DNA methylation during progression of lung adenocarcinoma

Q. H. Zhang, Dai, X. H., Dai, Z. M., and Cai, Y. N., “Genome-scale meta-analysis of DNA methylation during progression of lung adenocarcinoma”, vol. 14, pp. 9200-9214, 2015.

Identification of epigenetic alterations in tumors has become a common method for identifying genes critical to cancer development and progression. Thus, we identified DNA methylation alterations on the genome scale during lung adenocarcinoma (LADC) progression to understand the carcinogenic process and identify clinically relevant biomarkers. We found that epigenetic alterations in LADC mainly occur during the early stage of LADC progression, and there are no significant methylation differences between early-stage and late-stage LADCs.

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