Genetic variant

Association between the XPG gene Asp1104His polymorphism and lung cancer risk

B. Zhou, Hu, X. M., Wu, G. Y., Zhou, B., Hu, X. M., and Wu, G. Y., “Association between the XPG gene Asp1104His polymorphism and lung cancer risk”, vol. 15, p. -, 2016.

It has been suggested that the xeroderma pigmentosum complementation group G (XPG) gene Asp1104His polymorphism is linked to susceptibility to lung cancer. However, the results from the published studies are contradictory rather than conclusive. With this meta-analysis, we aimed to achieve a better understanding of the effects of the XPG gene Asp1104His polymorphism on lung cancer risk. We identified six eligible studies from five publications that included a total of 2293 lung cancer patients and 2586 controls.

Analyzing the association between XRCC1 c.1804C>A genetic variant and lung cancer susceptibility in the Chinese population

J. J. Jin, Wang, H. Q., Kuang, H. P., Kang, B. B., Liu, Y. H., Wang, J., Jin, J. J., Wang, H. Q., Kuang, H. P., Kang, B. B., Liu, Y. H., and Wang, J., “Analyzing the association between XRCC1 c.1804C>A genetic variant and lung cancer susceptibility in the Chinese population”, vol. 15, p. -, 2016.

Lung cancer is the most common cancer occurring worldwide. The human X-ray repair complementing group 1 (XRCC1) gene is one of the most important candidate genes that influence the susceptibility to lung cancer. The objective of this study was to analyze the potential association between the c.1804C>A genetic variant of XRCC1 and lung cancer susceptibility. A total of 703 subjects were recruited for this study. Genotyping of c.1804C>A genetic variant was performed using the created restriction site-polymerase chain reaction.

Association between RNF41 gene c.-206 T > A genetic polymorphism and risk of congenital heart diseases in the Chinese Mongolian population

Y. Zhang, Jin, S. Q., Li, W. X., Gao, G. Q., Zhang, K., Huang, J. L., Zhang, Y., Jin, S. Q., Li, W. X., Gao, G. Q., Zhang, K., and Huang, J. L., “Association between RNF41 gene c.-206 T > A genetic polymorphism and risk of congenital heart diseases in the Chinese Mongolian population”, vol. 15, p. -, 2016.

This study aimed to explore the association between ring finger protein 41 (RNF41) c.-206 T > A variant and susceptibility to congenital heart disease (CHD) in the Chinese Mongolian population. The association between RNF41 gene c.-206 T > A polymorphism and CHD was examined in two independent case-control studies consisting of 219 CHD patients and 208 healthy controls. Genotype was determined by direct sequencing of PCR products.

Tumor necrosis factor alpha gene -308G>A polymorphism association with the risk of esophageal cancer in a Han Chinese population

H. Zhao, Zhang, H. W., Zhang, T., Gu, X. M., Zhao, H., Zhang, H. W., Zhang, T., Gu, X. M., Zhao, H., Zhang, H. W., Zhang, T., Gu, X. M., Zhao, H., Zhang, H. W., Zhang, T., Gu, X. M., Zhao, H., Zhang, H. W., Zhang, T., and Gu, X. M., “Tumor necrosis factor alpha gene -308G>A polymorphism association with the risk of esophageal cancer in a Han Chinese population”, vol. 15. p. -, 2016.
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