Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study
“Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study”, vol. 14, pp. 9136-9144, 2015.
, Genetic variants of the POMC and PCSK1 genes cause severe obesity among patients in the early stages of childhood. This family-based study analyzed the links between single nucleotide polymorphisms (SNPs) in either the POMC or PCSK1 genes and obesity, as well as obesity-related traits among obese Thai children and their families. The variants rs1042571 and rs6713532 in the POMC gene in a sample of 83 obese children and their family members were investigated using polymerase chain reaction (PCR)-restriction fragment length polymorphism.