Genetic variant

Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study

S. Kulanuwat, Santiprabhob, J., Phonrat, B., Limwongse, C., Tungtrongchitr, A., Chongviriyaphan, N., and Tungtrongchitr, R., Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study, vol. 14, pp. 9136-9144, 2015.

Genetic variants of the POMC and PCSK1 genes cause severe obesity among patients in the early stages of childhood. This family-based study analyzed the links between single nucleotide polymorphisms (SNPs) in either the POMC or PCSK1 genes and obesity, as well as obesity-related traits among obese Thai children and their families. The variants rs1042571 and rs6713532 in the POMC gene in a sample of 83 obese children and their family members were investigated using polymerase chain reaction (PCR)-restriction fragment length polymorphism.

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