Gene polymorphisms

CYP19 gene polymorphisms and the susceptibility to breast cancer in Xinjiang Uigur women

L. Yang, Wang, X. Y., Li, Y. T., Wang, H. L., Wu, T., Wang, B., Zhao, Q., Jinsihan, D., and Zhu, L. P., CYP19 gene polymorphisms and the susceptibility to breast cancer in Xinjiang Uigur women, vol. 14, pp. 8473-8482, 2015.

In this study, the relationship between CYP19 gene polymorphisms and breast cancer in Xinjiang Uigur women was investigated. A case-control study was designed to compare 112 Uigur breast cancer patients with 139 Uigur healthy controls. Individuals were genotyped for the CYP19 rs10046 polymorphism using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP). Accordingly, the relationship between the rs10046 polymorphism and the susceptibility of Xinjiang Uigur women to breast cancer was analyzed.

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