Gene polymorphism

A study of the association between the connexin 40 rs35594137 polymorphism and atrial fibrillation in Xinjiang Chinese Han and Uygur populations

Y. Feng, Sun, J., Wang, L., and Hou, X. L., A study of the association between the connexin 40 rs35594137 polymorphism and atrial fibrillation in Xinjiang Chinese Han and Uygur populations, vol. 14, pp. 15705-15712, 2015.

Atrial fibrillation (AF) occurrence has a known genetic component. Many reports have revealed a correlation between gene mutation and AF, involving genes related to ion channels, connexin (Cx), and those within the angiotensin system. In this study, the cor­relation between the Cx 40 polymorphism (rs35594137) and AF was investigated in patients with AF in the Xinjiang, Turpan, and Kashi re­gions and in controls. The AF cohort included 122 patients (58 Han and 64 Uygur). The control subjects were recruited according to the 1:1 corresponding method and matched for age and gender.

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