Gene polymorphism

Analysis of CYP1A1 and COMT polymorphisms in women with cervical cancer

J. P. Kleine, Camargo-Kosugi, C. M., Carvalho, C. V., Silva, F. C., and Silva, I. D. C. G., Analysis of CYP1A1 and COMT polymorphisms in women with cervical cancer, vol. 14, pp. 18965-18973, 2015.

The aim of this case-control study was to obtain a comprehensive panel of genetic polymorphisms present only in genes (cytochrome P-450 1A1 - CYP1A1 and catechol-O-methyl transferase - COMT) within the metabolic pathway of sex steroids and determine their possible associations with the presence or absence of cervical cancer.

Association between the AGTR1 A1166C polymorphism and risk of IgA nephropathy: a meta-analysis

J. M. Xu, Song, X., Gao, F., and Wang, R., Association between the AGTR1 A1166C polymorphism and risk of IgA nephropathy: a meta-analysis, vol. 14, pp. 19371-19381, 2015.

Numerous studies have evaluated the association between the A1166C polymorphism in the angiotensin II type 1 receptor (AGTR1) gene and immunoglobulin A nephropathy (IgAN) risk. However, this relationship remains controversial. Our aim was to evaluate the relationship between this polymorphism and IgAN susceptibility by performing a meta-analysis. Articles were identified in the PubMed, Google Scholar, and China National Knowledge Infrastructure databases, and after selection, five eligible studies were included.

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