Gene networks

Gene networks as a tool to understand transcriptional regulation

D. Fernando Veiga, Vicente, F. Fernandes, and Bastos, G., Gene networks as a tool to understand transcriptional regulation, vol. 5, pp. 254-268, 2006.

Gene regulatory networks, or simply gene networks (GNs), have shown to be a promising approach that the bioinformatics community has been developing for studying regulatory mechanisms in biological systems. GNs are built from the genome-wide high-throughput gene expression data that are often available from DNA microarray experiments. Conceptually, GNs are (un)directed graphs, where the nodes correspond to the genes and a link between a pair of genes denotes a regulatory interaction that occurs at transcriptional level.

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