Gene expression profile

Transcriptional analysis of atrial and ventricular muscles from rats

Y. Zhi, Cao, Z., Li, Q. H., Li, X. L., Sun, Y., Zhang, T., Zhang, Q., Zhi, Y., Cao, Z., Li, Q. H., Li, X. L., Sun, Y., Zhang, T., Zhang, Q., Zhi, Y., Cao, Z., Li, Q. H., Li, X. L., Sun, Y., Zhang, T., and Zhang, Q., Transcriptional analysis of atrial and ventricular muscles from rats, vol. 15, p. -, 2016.

Previous studies have used microarray technology to explore gene expression differences between the atrium and the ventricle. However, selection criteria for the differentially expressed genes (DEGs) based only on either the fold change or the P value in these studies. Here, we aim to further identify the DEGs by setting a P value threshold of 2, which may yield more specific gene expression differences between the atrium and the ventricle.

MicroRNA screening and functional study of obliterative bronchiolitis in a rat model simulating lung transplantation

J. Wang, Cao, H., Hong, X., Chen, G. H., Fan, H. M., Li, Q. C., Liu, Z. M., and Li, K. F., MicroRNA screening and functional study of obliterative bronchiolitis in a rat model simulating lung transplantation, vol. 14, pp. 19309-19316, 2015.

The aim of this study was to provide the experimental basis for effective prevention and treatment of obliterative bronchiolitis (OB) by studying the changes on the microRNA (miRNA) expression profile after an orthotopic tracheal transplantation (OTT) simulating lung transplantation (LT). The OTT was performed on inbred rats to establish an OB animal model simulating LT, which was confirmed successful through pathological examination after 4 weeks.

Branches of NF-κb signaling pathway regulate hepatocyte proliferation in rat liver regeneration

C. F. Chang, Zhao, W. M., Mei, J. X., Zhou, Y., Pan, C. Y., Xu, T. T., and Xu, C. S., Branches of NF-κb signaling pathway regulate hepatocyte proliferation in rat liver regeneration, vol. 14, pp. 7643-7654, 2015.

Previous studies have demonstrated that the nuclear factor κB (NF-κB) pathway is involved in promoting cell proliferation. To further explore the regulatory branches and their sequence in the NF-κB pathway in the promotion of hepatocyte proliferation at the transcriptional level during rat liver regeneration, Rat Genome 230 2.0 array was used to detect the expression changes of the isolated hepatocytes.

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