Gene expression profile

Branches of the NF-κB signaling pathway regulate proliferation of oval cells in rat liver regeneration

W. M. Zhao, Qin, Y. L., Niu, Z. P., Chang, C. F., Yang, J., Li, M. H., Zhou, Y., Xu, C. S., Zhao, W. M., Qin, Y. L., Niu, Z. P., Chang, C. F., Yang, J., Li, M. H., Zhou, Y., Xu, C. S., Zhao, W. M., Qin, Y. L., Niu, Z. P., Chang, C. F., Yang, J., Li, M. H., Zhou, Y., and Xu, C. S., Branches of the NF-κB signaling pathway regulate proliferation of oval cells in rat liver regeneration, vol. 15, p. -, 2016.

The NF-kB (nuclear factor kB) pathway is involved in the proliferation of many cell types. To explore the mechanism of the NF-kB signaling pathway underlying the oval cell proliferation during rat liver regeneration, the Rat Genome 230 2.0 Array was used to detect expression changes of NF-kB signaling pathway-related genes in oval cells. The results revealed that the expression levels of many genes in the NF-kB pathway were significantly changed. This included 48 known genes and 16 homologous genes, as well as 370 genes and 85 homologous genes related to cell proliferation.

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