Gene expression

Methylation differences and expression profiles of the caprine DIO3 gene

H. Zhang, Jin, P. F., Niu, L. L., Li, L., Wang, L. J., Chen, Y., Zhang, G. J., Zhang, H. P., Zhong, T., Zhang, H., Jin, P. F., Niu, L. L., Li, L., Wang, L. J., Chen, Y., Zhang, G. J., Zhang, H. P., and Zhong, T., Methylation differences and expression profiles of the caprine DIO3 gene, vol. 15, p. -, 2016.

DIO3 gene encoding type 3 iodothyronine deiodinase is an imprinted gene, located in the DLK1-DIO3 (delta-like 1 homolog-type 3 iodothyronine deiodinase) imprinted domain, and is potentially involved in degrading excessive amounts of thyroid hormone to protect embryogenesis. However, the underlying regulatory mechanism of the imprinted DIO3 gene expression during fetal and neonatal development in goats has not been elucidated.

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