Gene expression

Gene expression profiling of somatic and pluripotent cells reveals novel pathways involved in reprogramming

Y. N. Cai, Dai, X. H., Zhang, Q. H., Hu, R., and Dai, Z. M., Gene expression profiling of somatic and pluripotent cells reveals novel pathways involved in reprogramming, vol. 14, pp. 12085-12092, 2015.

We investigated gene expression in embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, and fibroblasts. Microarray expression data sets obtained from the Gene Expression Omnibus were analyzed using the Partek software. Human genes from ES cells, iPS cells, and fibroblasts were ranked from low to high according to their expression levels. The gene expression mode in iPS cells was much more like the mode in ES cells, and the expression levels of fibroblast genes fluctuated more dramatically than those of iPS and ES cells.

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