Gastric cancer

Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population

M. Li, Li, R. J., Bai, H., Xiao, P., Liu, G. J., Guo, Y. W., Mei, J. Z., Li, M., Li, R. J., Bai, H., Xiao, P., Liu, G. J., Guo, Y. W., Mei, J. Z., Li, M., Li, R. J., Bai, H., Xiao, P., Liu, G. J., Guo, Y. W., and Mei, J. Z., “Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population”, vol. 15, p. -, 2016.

We did a case-control study to provide a more comprehensive evaluation of the association of the pre-miR-196a2 rs11614913 polymorphism with gastric cancer. Between January 2013 and December 2014, 182 patients newly diagnosed with primary gastric cancer and 182 control subjects were recruited at Zhengzhou People’s Hospital. For SNP genotyping, we used the Assay Designer 3.1 to design the primers of polymerase chain reaction.

Genetic variability of XRCC1 influences the treatment outcome of gastric cancer

H. Q. Hu, Wang, F., Du, X., Zhao, X. Z., Jin, Z., Hou, M. X., Hu, H. Q., Wang, F., Du, X., Zhao, X. Z., Jin, Z., and Hou, M. X., “Genetic variability of XRCC1 influences the treatment outcome of gastric cancer”, vol. 15, p. -, 2016.

We aimed to investigate the role of XRCC1 codon 194 (Arg>Trp), 280 (Arg>His), and 399 (Arg>Gln) polymorphisms in response to chemotherapy and the overall survival of gastric cancer patients. A total of 172 patients were recruited for our study between January 2010 and March 2012. Genotyping of the three XRCC1 codons was carried out by restriction fragment length polymorphism polymerase chain reaction.