Gastric cancer

Effect of cyclosporin A particles of varying diameters on gastric cancer cell apoptosis

X. L. Xing, Lu, Y., Qiu, H. L., Xing, X. L., Lu, Y., Qiu, H. L., Xing, X. L., Lu, Y., and Qiu, H. L., “Effect of cyclosporin A particles of varying diameters on gastric cancer cell apoptosis”, vol. 15, p. -, 2016.

Human health is significantly threatened by gastric cancer, which is the most common malignant tumor; although drastic, surgery is currently the only way to cure it. However, high recurrence rates and low survival rates are associated with the disease. Therefore, to improve the effectiveness of gastric cancer treatment and to increase the clinical cure rate, we investigated the effect of cyclosporin A particles of varying diameter on gastric cancer cell apoptosis.

Reduced expression of serum miR-204 predicts poor prognosis of gastric cancer

X. Chen, Liu, X. S., Liu, H. Y., Lu, Y. Y., Li, Y., Chen, X., Liu, X. S., Liu, H. Y., Lu, Y. Y., Li, Y., Chen, X., Liu, X. S., Liu, H. Y., Lu, Y. Y., and Li, Y., “Reduced expression of serum miR-204 predicts poor prognosis of gastric cancer”, vol. 15, p. -, 2016.

Deregulation of microRNAs (miRNAs) is implicated in the initiation and progression of gastric cancer (GC). Previous studies have demonstrated that miR-204 was downregulated in GC tissues. However, its expression profile in serum samples and its potential for clinical value remain unknown. Real-time PCR was performed to evaluate the expression level of serum miR-204 in patients with GC. The association between serum miR-204 expression level and the clinical outcome of GC was then investigated.

Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population

M. Li, Li, R. J., Bai, H., Xiao, P., Liu, G. J., Guo, Y. W., Mei, J. Z., Li, M., Li, R. J., Bai, H., Xiao, P., Liu, G. J., Guo, Y. W., Mei, J. Z., Li, M., Li, R. J., Bai, H., Xiao, P., Liu, G. J., Guo, Y. W., and Mei, J. Z., “Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population”, vol. 15, p. -, 2016.

We did a case-control study to provide a more comprehensive evaluation of the association of the pre-miR-196a2 rs11614913 polymorphism with gastric cancer. Between January 2013 and December 2014, 182 patients newly diagnosed with primary gastric cancer and 182 control subjects were recruited at Zhengzhou People’s Hospital. For SNP genotyping, we used the Assay Designer 3.1 to design the primers of polymerase chain reaction.

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